| ncRNA name | hsa-miR-146b-3p |
| ncRNA Category | miRNA |
| Disease name | diabetic retinopathy (DR) |
| Species | Homo sapiens |
| Tissues/Cell_line | vitreous; human monocyte cell line U937; human RECs |
| Methods | ELISA, immunofluorescence, qPCR, Western blot |
| Expression pattern | down-regulated |
| Functional description | Adenosine deaminase-2 is implicated in breakdown of the blood-retinal barrier (BRB) in DR through macrophages-derived cytokines. Inhibition of ADA2 by miR-146b-3p might be a useful tool to preserve BRB function in DR. |
| PubMed ID | 28170537 |
| Year | 2017 |
| Title | Adenosine Deaminase-2-Induced Hyperpermeability in Human Retinal Vascular Endothelial Cells Is Suppressed by MicroRNA-146b-3p. |
| Drug-related ncRNA | NO |
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